Markers for myofibroblasts in inflammatory gums pseudotumors

Authors: Ana Maria FILIOREANU*, Constantin COTRUTZ, Tudor PETREUŞ, Carmen Elena COTRUTZ
Affiliation: Department of Cell and Molecular Biology, University of Medicine and Pharmacy „Gr. T. Popa” Iasi

Read full article


ABSTRACT. We have investigated the presence of α-actin and vimentin in biological samples harvested from two patients one diagnosed with fibro-inflammatory epulis and one diagnosed peripheral giant cell granuloma. In the fibro-inflammatory epulis, labelling for vimentin was important for the connective cells in the deep chorion but positive vimentin cells were observed also near chronic inflammatory reaction. Actin immunolabelling was positive for the myofibroblasts in the deep chorion, in the smooth muscle cells in the mid-vessels walls or in the myofibroblasts near the imflammatory process.

Keywords: α-actin, vimentin, myofibroblast, imunolabelling, epulis