Plant extracts from meristematic tissues (foliar buds and shoots)

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Article Title:	Plant extracts from meristematic tissues (foliar buds and shoots): Antioxidant and therapeutic action
Authors:	Andreea Viorica Militaru1, Ioan Simedrea1, Iren Alexoi1, Camelia Peev*2, Elena Bernad1, Claudia-Crina Toma3
Affiliation:	1 „Victor Babeş” University of Medicine and Pharmacy, Timisoara, Romania, Faculty of Medicine 2 „Victor Babeş” University of Medicine and Pharmacy, Timisoara, Romania, Faculty of Pharmacy 3 „Vasile Goldiş” Western University of Arad, Romania, Faculty of Medicine, Pharmacy and Dental Medicine
Abstract:	Foliar buds form a new category of vegetal product, being used in modern phytotherapy, also known as gemmotherapy. Rheumatoid arthritis, often called RA, is a chronic (long-standing) disease that damages and eventually destroys the joints of the body. It has been used three types of bud extracts (Ribes nigrum, Buxus sempervirens, Vitis vinifera) with proved antirheumatic effects, during a period of 3 months. The success of treatment is checked by regular physical examinations and interviews. In all the patients we observed a clinical amelioration, permitting a slight reduction of the dose of the NSAIDs and the DMARDs.
Keywords:	foliar buds, juvenile rheumatoid arthritis, polyphenols, antioxidant activity
References:	European Pharmacopoeia 5th ed., Council of Europe – European Directorate for the Quality of Medicines, p. 221, 2005. Heinrich M., Barnes M., Gibbons S., Wiliamson. Phytotherapy and pharmacognosy, Edinburg- London- New York:, p.237, 2004. Hyun Ah Jung, Da-Mi Jeong, Hae Young Chung et al. Re-evaluation of the Antioxidant Prenylated Flavonoids from the Roots of Sophora flavescens, Biol. Pharm. Bull.; Vol. 31: 908-915, 2008. Neacşu M.,C. Socaciu, M. Tămaş, C. Blidar(Peev)- HPLC separation systems of flavonoids from buds of diverse medicinal plants.Buletinul USAMV-CN, Cluj-Napoca.; 57: 45-51, 2002. Peev C., Vlase L., Antal D., Kaycsa A., Dehelean C.- Phytochemical profile of the foliar buds of black currant (Ribes nigrum), Timisoara Medical Journal; 56(2): 212-16, 2006. Pitera F., Compendio di Gemmoterapia Clinica, Editore de Ferrari, , p.349- 360, 510-517, 614- 618, 2000. Peev C., Mugurii foliari, materii prime în gemoterapie, Timişoara, Ed.Mirton:, 164-167, 2007. Peev C., Antal D., Vlase L., Dehelean C., Szabadai Z. The content in polyphenols of silver linden (Tilia tomentosa) foliar buds. Farmacia; 2: 79- 87, (2006).
*Correspondence:	Camelia Peev, Faculty of Pharmacy UMF Timisoara „Victor Babeş” University of Medicine and Pharmacy, P-ta Eftimie Murgu nr.2, 300041,Timişoara, cameliapeev@yahoo.com