Molecular detected of ghrelin receptor gene in Iraqi male goats
May 6, 2026
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| Article Title: | Molecular detected of ghrelin receptor gene in Iraqi male goats |
| Authors: | Mohammed M.K., Habib H.N., Kassem W.Y. |
| Affiliation: | PhD Student, Department of Animal Production, College of Agriculture, University of Basrah, Iraq, Maysan 00964 Department of Animal Production / College of Agriculture, University of Basrah, Iraq, Basrah 00964 Department of Animal Production / College of Agriculture, University of Basrah, Iraq, Basrah 00964 |
| Abstract: | Goats are vital livestock for milk, meat, and hair production across Asia and Africa, yet their genetic improvement has often been neglected. The growth hormone secretagogue receptor (GHSR) gene, critical in regulating metabolism and productivity through ghrelin signaling, is of particular interest for enhancing livestock performance. This study aimed to investigate the polymorphisms of the GHSR gene in Iraqi local goats. Eighteen male goats were sampled at the College of Agriculture, University of Basrah. DNA was extracted, amplified via PCR, and sequenced for analysis. The results revealed two novel genetic variants of the GHSR gene not previously recorded in global databases, showing 99.45% similarity to the San Clemente goat sequence (USA). Multiple sequence alignment demonstrated distinct mutations, including both silent and missense mutations, suggesting potential functional impacts on gene expression and protein function. These findings highlight the genetic diversity of Iraqi goats and suggest that GHSR polymorphisms may serve as valuable molecular markers for future breeding and productivity enhancement programs. Further research is needed to associate these genetic variations with physiological and productive traits. |
| Keywords: | Iraqi goats, gene polymorphism, molecular detected, ghrelin receptor gene, molecular markers. |
| *Correspondence: | Hassan Nima Habib, Department of Animal Production / College of Agriculture, University of Basrah, Iraq, Basra, Tel. 009647801105643, email: hassan.nima@uobasrah.edu.iq |
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