Assessing the toxic, behavioral, and reproductive impacts of Euphorbia bupleuroides on Drosophila melanogaster
January 26, 2026
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| Article Title: | Assessing the toxic, behavioral, and reproductive impacts of Euphorbia bupleuroides on Drosophila melanogaster |
| Authors: | Habbachi S., Boublata N.E., Tabirca A.I., Djaouahdou R., Habbachi W., Benhissen S., Tahraoui A. |
| Affiliation: | Laboratory of Applied Neuroendocrinology. Badji Mokhtar – Annaba University P.O Box.12, Annaba-23000 Algeria Faculty of Economics, Valahia University of Targoviste, 130004 Targoviste, Romania Research Laboratory in Innovation and Economic and Financial Analysis. Badji Mokhtar – Annaba University P.O Box.12, Annaba-23000 Algeria Department of Biology, Faculty of Science-Université Med Boudiaf, M’Sila 28000 |
| Abstract: | This study explores the insecticidal potential of the Saharan species Euphorbia bupleuroides by assessing the effects of its aqueous leaf extract on Drosophila melanogaster. The extract exhibited strong bioactivity, inducing complete mortality in larvae and males and high mortality in females. Feeding assays revealed a disruption of larval chemosensory responses, with treated larvae losing their ability to discriminate between nutritive substrates. At the behavioural level, the extract significantly altered courtship sequences and sharply reduced mating success, demonstrating an inhibitory effect on reproductive signalling. Oviposition experiments showed that females, whether treated or untreated, prefer the control substrate, confirming a marked repellent effect of the extract. Together, these findings highlight the potent insecticidal and behavioural-modulating properties of E. bupleuroides and support its potential use in environmentally sustainable, plant-based pest management strategies. |
| Keywords: | biopesticide, Ruta chanlepnsis L, Wistar rat, aqueous extract, ethanolic extract. |
| *Correspondence: | Sarra Habbachi, Laboratory of Applied Neuroendocrinology. Badji Mokhtar – Annaba University P.O Box.12, Annaba-23000 Algeria, phone number: +213 (0) 661 29 92 37, email: sarra.habbachi@univ-annaba.dz |
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