The evaluation of the effectiveness of phytoestrogens in improving, reduction or suppression of the climacteric symptomatology

November 17, 2014

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Article Title:	The evaluation of the effectiveness of phytoestrogens in improving, reduction or suppression of the climacteric symptomatology
Authors:	Tit D.M., Lazar L., Bungau S., Pallag A., Bei D.
Affiliation:	Oradea University, Faculty of Medicine and Pharmacy, 23 N. Jiga St., Oradea, Romania, Oradea University, Faculty of Medicine and Pharmacy, 10 Decembrie 1 St St., Oradea, Romania,
Abstract:	Although menopause is a physiological event that occurs in the life of every woman, endocrine changes associated with it can cause major changes in the health status and psychosocial life in a significant number of women.This study evaluates the effectiveness of the phytoestrogens administered as OTC preparations available in pharmacies, concerning the specific menopausal symptoms and is conducted on a total of 230 postmenopausal women randomized into two study groups, group 1-124 women who received different preparations OTC containing phytoestrogens derived from soy, red clover, Cimicifugaracemosa or combinations of plants in various doses recommended by the practitioner and group 2-106 women who received no preparation.The assessment of the symptoms was made based on MRS questionnaire (The Menopausal Rating Scale). From the comparative analysis of the two groups, it was found that phytoestrogens facilitate symptom relief and even their extinction, particularly in the first 6 months.
Keywords:	phythoestrogens, climacteric symptoms, MRS, Questionnaires
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*Correspondence:	Delia-Mirela Ţiţ, Oradea University, Faculty of Medicine and Pharmacy, 23 N. Jiga St., Oradea, Romania, e-mail: mirela_tit@yahoo.com; Liviu Lazăr, Oradea University, Faculty of Medicine and Pharmacy, 10 Decembrie 1 St St., Oradea, Romania, e-mail: lvlazar@yahoo.com

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