Evaluation of biocompatibility of composite biomaterial with anti-inflammatory action, and stimulating tissue recovery process
November 17, 2014
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| Article Title: | Evaluation of biocompatibility of composite biomaterial with anti-inflammatory action, and stimulating tissue recovery process |
| Authors: | Iordachel C., Berteanu E., Zuav A.-L., Enache M.-I., Dobre A.-M., Manoiu S., Paraschiv M., Tcacenco L. |
| Affiliation: | Department of Biomaterials & Bioproducts, National Institute R&D for Biological Sciences, Address: 296 Splaiul Independentei, 060031-Bucharest, Romania |
| Abstract: | The paper refers to a bioactive matrix in membrane shape, with a thickness of 0.5 – 1.0 mm, and consisting of gelatine, chitosan, and a-chymotrypsin, with or without addition of glutaraldehyde as a cross-linking agent. The bioproduct is a biomaterial with biomedical applications as biocompatible membrane with anti-inflammatory action due to coupling of the proteolytic enzyme. Bioproducts have complex implications in the treatment of traumatized tissue, accelerating the pus cleansing of infected wound, blood clots and other cellular debris, secretions liquefaction and cleansing of necrotic tissue, and also stimulating tissue regeneration and a faster healing of open infected wounds. In order to establish the influence of crosslinking process and membrane’s thickness on mechanical properties, ultrastructural studies were carried out on obtained biomaterials by electron microscopy analysis. To demonstrate the biological qualities of new enzymatic biomaterials, the membrane’s biological effect was analyzed in a cell culture model (mouse fibroblasts NCTC). |
| Keywords: | biomaterial, chitosan, gelatine, proteolytic enzyme, anti-inflammatory composite. |
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| *Correspondence: | Catalin Iordachel, National Institute R&D for Biological Sciences, Department of Biomaterials & Bioproducts, no. 296 Splaiul Independentei, 060031-Bucharest, Romania, Tel./Fax +40 (21)- 220.79.09, e-mail: cataliniordachel@yahoo.com |
Dosage of some organic compounds in the leaves of the Sedum telephium ssp. maximum l. plants harvested from nature compared with plants obtained on the culture of Murashige – Skoog supplemented with growth regulator
Selection of an efficient chondroitin sulfate-liposome delivery system as chondroprotective agent for local inflammation treatment
Autologous stem cell therapy for acute myocardial infarction with severe systolic dysfunction – protocol and feasibility at 1 month follow-up – Bucharest experience
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Cultivation- removed
November 17, 2014
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| Article Title: | Cultivation of a miscanthus giganteus on soils polluted with heavy metals and the use of the resulted biomass |
| Authors: | Grama B.G., Pavel B.P., Sand C., Pop M.R., Barbu C.H. |
| Affiliation: | National Institute of Biological Science Research and Development (INCDSB), Bucharest, Romania; Clinical Institute Fundeni, Center of Hematology & Bone Marrow Transplantation ’’St. Berceanu’’, Bucharest; “Vasile Goldis” Western University of Arad, Faculty of Natural Sciences, Arad, Romania |
| Abstract: | The paper presents our results in cultivation on soils polluted with heavy metals (Pb, Cd) of Miscanthus sinensis x giganteus, a sterile hybrid, as well as the tests we have performed for the use of the stems cropped after two years. The results are very encouraging and we expect more and more farmers to cultivate this plant, with benefit for them and for environment. |
| Keywords: | polycythemia vera; PV; rbcs, red blood cells; erythrocyte viability; phosphatidylserine exposure;caspase-3; caspase-8; Annexin-V; Calcein-AM; flow cytometry |
| References: | Antofie M, Constantinovici D, Pop M, Iagaru P, Sand, C, Ciortea G, Theoretical methodology for assessing the status of conservation of croplandraces in Romania. Analele Universitatii din Oradea – Fascicula Biologie, 17(2), 313-317, 2010. Barbu CH, Sand C, Oprean L, Phytoremediation of metal-contaminated sites. Eds. Morel JL, Echevarria G, Dordrecht, The Netherlands, Springer,319-326, 2006. Barbu CH, Grovu R, Contaminated Soils, Vol. 6, eds. Kostecki, PK, Calabrese EJ, Dragun, J, Amherst, MA, CRC Press, 69-78, 2001. Barbu CH, Pavel BP, Sand C, Pop MR, Proceedings of the 9th Int. Symp. of Roumanian Academy – October 16-17, Cluj-Napoca, Romania, 21-24,2009. Collura S, Azambre B, Finqueneisel G, Zimny T, Weber JV, Environ. Chem. Lett., 4, 75-78, 2005. Constantinescu L, Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Agriculture, 65 (2), 345-348, 2008. Dickinson NM, Baker AJM, Doronila A, Laidlaw S, Reeves RD, Int. J. Phytorem, 11 (2), 97-114, 2009. Dumitru M, Vrinceanu N, Motelica M, Proceedings of the COST 837 Meeting, Bordeaux, France, 2002. Dumitru M, Country Report-Romania, 2004. Frühwirth P, Liebhard P, Miscanthus sinensis ‟Giganteus‟ – Chinaschilf als nachwachsender Rohstoff. Landwirtschaftskammer Österreich und Ländliches Fortbildungsinstitut Österreich, 2004. Jones MB, Walsh M, Miscanthus for energy and fibre. London, James & James Publishers, 2001. Lacatusu R, Lacatusu AR, Carpath. J. of Earth and Environmental Sciences, 3 (2), 115-129, 2008. Pyter R, Voigt T, Heaton E, Dohleman F, Long S, Issues in new crops and new uses. Eds. Janick J and Whipkey A, Alexandria VA, ASHS Press., 2007. |
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Nutritional profile of Balanites aegyptiaca flower
The histology and mucin histochemistry of the farmed juvenile african catfish digestive tract (Clarias gariepinus b)
Potato germplasm vitropreservation, using light emitting diodes as light source
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