H1N1-like infections in pregnant women


H1N1-like infections in pregnant women

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Title: H1N1-like infections in pregnant women
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Article_Title: H1N1-like infections in pregnant women
Authors: Florin Szasz, Tiberiu Pop, Rita Herczegh
Affiliation: 1 University of Oradea, Faculty of Medicine and Pharmacy, Obstetrics-Gynecology Department
2 Clinical Hospital of Obstetrics-Gynecology Oradea
Abstract: The Pandemic H1N1/09 virus is a swine origin Influenza A virus subtype H1N1 virus strain responsible for the 2009 flu pandemic. While only mild symptoms are experienced by the majority of people, some patients, who in the following article will be considered as coming from risk groups, can develop more severe complications, even leading to death. Risk groups being considered: asthmatics, diabetics, obese or immune compromised patients, children with neurodevelopmental conditions, and most important from our point of view, pregnant women. In the next lines we are going to present two clinical cases of pregnant women, both presented in our hospital, supposed to have AH1N1 viral infection and treated in consequence, but unfortunately both ended malevolent as result of the severe and very rapid deterioration of their status. Although the two cases were similar as evolution and ending, there were also important differences between them, which can guide us for the future in investigating and treating this kind of pathology.
Keywords: AH1N1 virus, pregnancy, respiratory distress, differential diagnose
References: Centers for Disease Control and Prevention. Hospitalized patients with novel influenza A (H1N1) virus infection-California, April-May, 2009. MMWR Morb Mortal Wkly Rep 2009; 58: 536–41.
Centers for Disease Control and Prevention. Human infection with swine influenza virus-Wisconsin. MMWR Morb Mortal Wkly Rep 1988; 37: 661–63.
Centers for Disease Control and Prevention. Novel influenza A(H1N1) virus infections in three pregnant women—United States, April–May, 2009. MMWR Morb Mortal Wkly Rep 2009;58: 497–500.
Dodds L, McNeil SA, Fell DB, et al. Impact of influenza exposure on rates of hospital admissions and physician visits because of respiratory illness among pregnant women. CMAJ 2007;176: 463–68.
Freeman DW, Barno A. Deaths from Asian influenza associated with pregnancy. Am J Obstet Gynecol 1959; 78: 1172–75.
Harris JW. Influenza occurring in pregnant women. JAMA 1919;72: 978–80.
McKinney WP, Volkert P, Kaufman J. Fatal swine influenza pneumonia during late pregnancy. Arch Intern Med 1990
Neuzil KM, Reed GW, Mitchel EF, Simonsen L, Griffi n MR. Impact of influenza on acute cardiopulmonary hospitalizations in pregnant women. Am J Epidemiol 1998; 148: 1094–102.
Novel Swine-Origin Infl uenza A (H1N1) Virus Investigation Team.Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009; 361: 1–10.
Nuzum JW, Pilot I, Stangl FH, Bonar BE. 1918 pandemic influenza and pneumonia in a large civil hospital. IMJ Ill Med J 1976; 150: 612–16.
Zarocostas J. World Health Organization declares A (H1N1)influenza pandemic. BMJ 2009; 338: b2425.
Read_full_article: pdf/21-2011/21-1-2011/SU21-1-2011Szasz.pdf
Correspondence: Cristian Florin Szasz, Clinical Hospital of Obstetrics – Gynecology, 50-52 Clujului st, Oradea 410053, Romania, email: szasz.florin@yahoo.com

Read full article
Article Title: H1N1-like infections in pregnant women
Authors: Florin Szasz, Tiberiu Pop, Rita Herczegh
Affiliation: 1 University of Oradea, Faculty of Medicine and Pharmacy, Obstetrics-Gynecology Department
2 Clinical Hospital of Obstetrics-Gynecology Oradea
Abstract: The Pandemic H1N1/09 virus is a swine origin Influenza A virus subtype H1N1 virus strain responsible for the 2009 flu pandemic. While only mild symptoms are experienced by the majority of people, some patients, who in the following article will be considered as coming from risk groups, can develop more severe complications, even leading to death. Risk groups being considered: asthmatics, diabetics, obese or immune compromised patients, children with neurodevelopmental conditions, and most important from our point of view, pregnant women. In the next lines we are going to present two clinical cases of pregnant women, both presented in our hospital, supposed to have AH1N1 viral infection and treated in consequence, but unfortunately both ended malevolent as result of the severe and very rapid deterioration of their status. Although the two cases were similar as evolution and ending, there were also important differences between them, which can guide us for the future in investigating and treating this kind of pathology.
Keywords: AH1N1 virus, pregnancy, respiratory distress, differential diagnose
References: Centers for Disease Control and Prevention. Hospitalized patients with novel influenza A (H1N1) virus infection-California, April-May, 2009. MMWR Morb Mortal Wkly Rep 2009; 58: 536–41.
Centers for Disease Control and Prevention. Human infection with swine influenza virus-Wisconsin. MMWR Morb Mortal Wkly Rep 1988; 37: 661–63.
Centers for Disease Control and Prevention. Novel influenza A(H1N1) virus infections in three pregnant women—United States, April–May, 2009. MMWR Morb Mortal Wkly Rep 2009;58: 497–500.
Dodds L, McNeil SA, Fell DB, et al. Impact of influenza exposure on rates of hospital admissions and physician visits because of respiratory illness among pregnant women. CMAJ 2007;176: 463–68.
Freeman DW, Barno A. Deaths from Asian influenza associated with pregnancy. Am J Obstet Gynecol 1959; 78: 1172–75.
Harris JW. Influenza occurring in pregnant women. JAMA 1919;72: 978–80.
McKinney WP, Volkert P, Kaufman J. Fatal swine influenza pneumonia during late pregnancy. Arch Intern Med 1990
Neuzil KM, Reed GW, Mitchel EF, Simonsen L, Griffi n MR. Impact of influenza on acute cardiopulmonary hospitalizations in pregnant women. Am J Epidemiol 1998; 148: 1094–102.
Novel Swine-Origin Infl uenza A (H1N1) Virus Investigation Team.Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009; 361: 1–10.
Nuzum JW, Pilot I, Stangl FH, Bonar BE. 1918 pandemic influenza and pneumonia in a large civil hospital. IMJ Ill Med J 1976; 150: 612–16.
Zarocostas J. World Health Organization declares A (H1N1)influenza pandemic. BMJ 2009; 338: b2425.
*Correspondence: Cristian Florin Szasz, Clinical Hospital of Obstetrics – Gynecology, 50-52 Clujului st, Oradea 410053, Romania, email: szasz.florin@yahoo.com