Comparative microbiological activity of volatile oils from anethum graveolens species

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Article Title:	Comparative microbiological activity of volatile oils from anethum graveolens species
Authors:	Alina Ortan, Mariana Ferdes, Cristina Dinu Pirvu
Affiliation:	University Politehnica of Bucharest, Bucharest, Romania
Abstract:	The aim of this paper was to test the antifungal activity of volatile oils extracted from Anethi fructus, Anethi flores and Anethi folium using disk diffusion method, compared with an antifungal drug, miconazole, against Candida albicans reference strain. Three tests were made of antifungal activity, in identical conditions, at intervals of 1 week. We also tested the antifungal activity of presumed active components in the form of oily solutions, in concentrations equal to those of volatile oil from flower and leaf respectively, as well as the antifungal activity of volatile oil entrapped in a liposomal formulation. It was found that both flowers and fruits showed good antifungal activity against C. albicans strain, while the volatile oil of the leaves was not active. It was also observed that oily solution containing the appropriate concentration of carvone in the fruit oil has antifungal activity, but oily solutions containing appropriate concentrations of limonene from flowers, respectively fruits do not have antifungal activity.
Keywords:	Anethi fructus, Anethi flores, Anethi folium, volatile oil, microbiological activity
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*Correspondence:	Cristina Dinu Pirvu, University of Medicine and Pharmacy „Carol Davila”, Dionisie Lupu st, no 37, sector 1, postal code 020022, Bucharest, Romania, tel: 40.21 318.0719; fax: +40.21 318.0721; email: ecristinaparvu@yahoo.com