Antimitotic activity of saponins obtained from Anagalis arvensis


Antimitotic activity of saponins obtained from Anagalis arvensis

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Title: Antimitotic activity of saponins obtained from Anagalis arvensis
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Article_Title: Antimitotic activity of saponins obtained from Anagalis arvensis
Authors: Luciana Dobjanschi, Mariana Mureşan, Angela Antonescu, Mihaela Zdrîncă, Ildiko Szabo, Mircea Tămaş
Affiliation: 1 University of Medicine and Pharmacy Oradea, Faculty of Pharmacy
2 University of Medicine and Pharmacy „Iuliu Hatieganu”, Cluj-Napoca
Abstract: Because of the extended use of plant derived drugs (Tămaş, 1995), we studied some plant
extracts and substances obtained from plants (Tămaş et al., 1978 et al., Tămaş et al., 1983). Natural drugs are used on an extended basis because of limited secondary effects and adverse reactions. In our present paper we tested the action of saponins obtained from Anagalis arvensis (Boiteanu et all, 1964, Glombitza and Kurth, 1987, Amoros and Girre, 1987) on the growth of meristems of Triticum sp. and cellular division. Tests with saponins obtained from Anagalis arvensis inhibit the growth of Triticum sp. meristems, and cellular division, concluding that these saponins may be included in the antimitotic medication group (Schonfelder and Schonfelder, 2004).
Keywords: saponins, anagalis arvensis, antimitotics
References: Amoros M., Girre R. L., Structure of two antiviral triterpene saponins from Anagallis arvensis,
Phytochemistry, 26, (3), pp. 787-791, 1987.
Arieşan Maria, Pitea Michaela, Cojocaru Zenaida, Acţiunea pe teste fitobiologice a unor derivaţi 7-
R-flavonici, Symposium flavonoide, Cluj-Napoca VI., p. 54, 1984.
Boiteau P., Pasich B., Ratsimamanga r.a., Les triterpenoides en physiologie vegetale et animale, Gauthier-Villars, Paris, 1964.
Glombitza K.W. und Kurth H., Die Struktur einiger Triterpensaponine aus Anagallis arvensis, Planta Medica, 53 (6), p. 509, 1987.
Schönfelder I., Schönfelder P., Das neue handbuch der Heilpflanzen, botanik arzneidrogen Wirkstoffe
anwendungen, Stuttgart, 420, 2004.
Şerbănescu-Jitariu Gabriela, Andrei Maria, Rădulescu- Mitroiu Natalia, Petria Elena, Practicum de
biologie vegetală, Ed. Ceres, Buc., pp. 158-225, 1983.
Tarnavschi ION T., Şerbănescu-Jitariu Gabriela, Mitroiu Rădulescu Natalia, rădulescu Didona,
Practicum de morfologie şi anatomie vegetală, Bucureşti, 1974.
Tarnavschi Ion T., Şerbănescu-Jitariu Gabriela, Mitroiu.Rădulescu Natalia, Rădulescu Didona,
Practicum de morfologie şi anatomie vegetală, ediţia a 2-a, Bucureşti, 1981.
Tămaş M., Actualităţi în fitoterapie: taxolul, Terapeutica, vol. 2, 3, 40, 1995.
Tămaş M., Hodişan V., Grecu L. Făgărăşanu E., Baciu M., Muică I., Cercetări asupra saponinelor
triterpenice din plante medicinale indigene, Studii şi cercetări de biochimie, 21, (1), pp. 89-94, 1978.
Tămaş M., Hodişan Viorica, Saponine triterpenice de interes terapeutic, Practica farmaceutică, p. 57, 1983.
Tămaş M., Lucrări practice de biologie celulară, Lit. IMF Cluj-Napoca, 1976
Read_full_article: pdf/18-2008/SU08Dobjanschi2.pdf
Correspondence: Dobjanschi Luciana, Facultatea de Medicina si Farmacie Oradea, Catedra de Biochimie, P-ta 1 Decembrie nr. 10, Tel. 0723-766789, email: dobjanschil@yahoo.com

Read full article
Article Title: Antimitotic activity of saponins obtained from Anagalis arvensis
Authors: Luciana Dobjanschi, Mariana Mureşan, Angela Antonescu, Mihaela Zdrîncă, Ildiko Szabo, Mircea Tămaş
Affiliation: 1 University of Medicine and Pharmacy Oradea, Faculty of Pharmacy
2 University of Medicine and Pharmacy „Iuliu Hatieganu”, Cluj-Napoca
Abstract: Because of the extended use of plant derived drugs (Tămaş, 1995), we studied some plant
extracts and substances obtained from plants (Tămaş et al., 1978 et al., Tămaş et al., 1983). Natural drugs are used on an extended basis because of limited secondary effects and adverse reactions. In our present paper we tested the action of saponins obtained from Anagalis arvensis (Boiteanu et all, 1964, Glombitza and Kurth, 1987, Amoros and Girre, 1987) on the growth of meristems of Triticum sp. and cellular division. Tests with saponins obtained from Anagalis arvensis inhibit the growth of Triticum sp. meristems, and cellular division, concluding that these saponins may be included in the antimitotic medication group (Schonfelder and Schonfelder, 2004).
Keywords: saponins, anagalis arvensis, antimitotics
References: Amoros M., Girre R. L., Structure of two antiviral triterpene saponins from Anagallis arvensis,
Phytochemistry, 26, (3), pp. 787-791, 1987.
Arieşan Maria, Pitea Michaela, Cojocaru Zenaida, Acţiunea pe teste fitobiologice a unor derivaţi 7-
R-flavonici, Symposium flavonoide, Cluj-Napoca VI., p. 54, 1984.
Boiteau P., Pasich B., Ratsimamanga r.a., Les triterpenoides en physiologie vegetale et animale, Gauthier-Villars, Paris, 1964.
Glombitza K.W. und Kurth H., Die Struktur einiger Triterpensaponine aus Anagallis arvensis, Planta Medica, 53 (6), p. 509, 1987.
Schönfelder I., Schönfelder P., Das neue handbuch der Heilpflanzen, botanik arzneidrogen Wirkstoffe
anwendungen, Stuttgart, 420, 2004.
Şerbănescu-Jitariu Gabriela, Andrei Maria, Rădulescu- Mitroiu Natalia, Petria Elena, Practicum de
biologie vegetală, Ed. Ceres, Buc., pp. 158-225, 1983.
Tarnavschi ION T., Şerbănescu-Jitariu Gabriela, Mitroiu Rădulescu Natalia, rădulescu Didona,
Practicum de morfologie şi anatomie vegetală, Bucureşti, 1974.
Tarnavschi Ion T., Şerbănescu-Jitariu Gabriela, Mitroiu.Rădulescu Natalia, Rădulescu Didona,
Practicum de morfologie şi anatomie vegetală, ediţia a 2-a, Bucureşti, 1981.
Tămaş M., Actualităţi în fitoterapie: taxolul, Terapeutica, vol. 2, 3, 40, 1995.
Tămaş M., Hodişan V., Grecu L. Făgărăşanu E., Baciu M., Muică I., Cercetări asupra saponinelor
triterpenice din plante medicinale indigene, Studii şi cercetări de biochimie, 21, (1), pp. 89-94, 1978.
Tămaş M., Hodişan Viorica, Saponine triterpenice de interes terapeutic, Practica farmaceutică, p. 57, 1983.
Tămaş M., Lucrări practice de biologie celulară, Lit. IMF Cluj-Napoca, 1976
*Correspondence: Dobjanschi Luciana, Facultatea de Medicina si Farmacie Oradea, Catedra de Biochimie, P-ta 1 Decembrie nr. 10, Tel. 0723-766789, email: dobjanschil@yahoo.com