Correlations between brain lesions, risk factors and age, in vascular dementia

Correlations between brain lesions, risk factors and age, in vascular dementia

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Title: Correlations between brain lesions, risk factors and age, in vascular dementia
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Article_Title: Correlations between brain lesions, risk factors and age, in vascular dementia
Authors: Elisaveta Ligia Piros, Gheorghe Ciobanu, Anca Mustea, Sanda Maria Deme, Harry Grossmann, Delia Marina Podea
Affiliation: Faculty of Medicine, Pharmacy and Dental Medicine, “Vasile Goldis” Western University of Arad
Abstract: In Romania, dementia is under diagnosed due to lack of information, which makes the symptoms unrecognizable. Sometimes, even when symptoms are recognized, the patient is not taken to the doctor, because the symptoms he or she exhibits are considered normal consequences of aging. Cardiovascular pathology and its associated risk factors lead to structural and functional brain changes. Cognitive impairment occurring within the general phenomenon of human aging is related to a variety of genetic, morphological, biological, socio-cultural and individual and in turn has major impact on morbidity and autonomy of the elderly. A better understanding of the nature of the disease, its causation and early detection of brain changes can lead to early diagnosis of vascular dementia and the establishment of a prevention and treatment program that will help reduce the severity of dementia or morbidity. Our world is dominated by economic criteria and a crucial component is cost-effectiveness. Therefore it is necessary, today more than ever, to choose useful and sufficient high quality examinations in order to give up costly and often unnecessary diagnostic exams.
Keywords: computed tomography, acute ischemic stroke, vascular dementia, risk factors, prevention
References: American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th ed. (DSMIV). Washington DC: APA; 1994
Brunnstrom HR, Englund EM. Cause of death in patients with dementia disorders. Eur J Neurol. Apr 2009;16(4):488-92.
Ciobanu Gheorghe, Calin Ciobanu, Radiodiagnostic clinic ed.III, editura Tiparnita 2011,
Kaplan & Sadock’s, Comprehensive Textbook of Psychiatry, Eighth Edition, Vol. I, Lippincott Williams & Wilkins, 2005
Rusanen M, Kivipelto M, Quesenberry CP Jr, Zhou J, Whitmer RA. Heavy Smoking in Midlife and Long-term Risk of Alzheimer Disease and Vascular Dementia. Arch Intern Med. Oct 25 2010;
Vercambre MN, Grodstein F, Manson JE, Stampfer MJ, Kang JH. Physical activity and cognition in women with vascular conditions. Arch Intern Med. Jul 25 2011;171(14):1244-50.
Wardlaw JM, Farrall AJ, Perry D, von Kummer R, Mielke O, Moulin T, Ciccone A, Hill M: Factors influencing the detection of early CT signs of cerebral ischemia: an internet-based, international multiobserver study. Stroke 2007;38:1250-1256.
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Article Title: Correlations between brain lesions, risk factors and age, in vascular dementia
Authors: Elisaveta Ligia Piros, Gheorghe Ciobanu, Anca Mustea, Sanda Maria Deme, Harry Grossmann, Delia Marina Podea
Affiliation: Faculty of Medicine, Pharmacy and Dental Medicine, “Vasile Goldis” Western University of Arad
Abstract: In Romania, dementia is under diagnosed due to lack of information, which makes the symptoms unrecognizable. Sometimes, even when symptoms are recognized, the patient is not taken to the doctor, because the symptoms he or she exhibits are considered normal consequences of aging. Cardiovascular pathology and its associated risk factors lead to structural and functional brain changes. Cognitive impairment occurring within the general phenomenon of human aging is related to a variety of genetic, morphological, biological, socio-cultural and individual and in turn has major impact on morbidity and autonomy of the elderly. A better understanding of the nature of the disease, its causation and early detection of brain changes can lead to early diagnosis of vascular dementia and the establishment of a prevention and treatment program that will help reduce the severity of dementia or morbidity. Our world is dominated by economic criteria and a crucial component is cost-effectiveness. Therefore it is necessary, today more than ever, to choose useful and sufficient high quality examinations in order to give up costly and often unnecessary diagnostic exams.
Keywords: computed tomography, acute ischemic stroke, vascular dementia, risk factors, prevention
References: American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th ed. (DSMIV). Washington DC: APA; 1994
Brunnstrom HR, Englund EM. Cause of death in patients with dementia disorders. Eur J Neurol. Apr 2009;16(4):488-92.
Ciobanu Gheorghe, Calin Ciobanu, Radiodiagnostic clinic ed.III, editura Tiparnita 2011,
Kaplan & Sadock’s, Comprehensive Textbook of Psychiatry, Eighth Edition, Vol. I, Lippincott Williams & Wilkins, 2005
Rusanen M, Kivipelto M, Quesenberry CP Jr, Zhou J, Whitmer RA. Heavy Smoking in Midlife and Long-term Risk of Alzheimer Disease and Vascular Dementia. Arch Intern Med. Oct 25 2010;
Vercambre MN, Grodstein F, Manson JE, Stampfer MJ, Kang JH. Physical activity and cognition in women with vascular conditions. Arch Intern Med. Jul 25 2011;171(14):1244-50.
Wardlaw JM, Farrall AJ, Perry D, von Kummer R, Mielke O, Moulin T, Ciccone A, Hill M: Factors influencing the detection of early CT signs of cerebral ischemia: an internet-based, international multiobserver study. Stroke 2007;38:1250-1256.
*Correspondence: